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ChIP-on-chip, also known as genome-wide location analysis, is a technique for isolation and identification of the DNA sequences occupied by specific DNA binding proteins in cells. These binding sites may indicate functions of various transcriptional r
egulators and help identify their target genes during animal development and disease progression. The identified binding sites may also be used as a basis for annotating functional elements in genomes. The types of functional elements that one can ident
ify using ChIP-on-chip include promoters, enhancers, repressor and silencing elements, insulators, boundary elements, and sequences that control DNA replication. The ChIP-on-chip is a technological platform used by the ENCODE consortium to map functional
elements in the human genome. Please click on the picture above to find information on ChIP-on-chip literature, protocols, ChIP-grade antibodies, data analysis software, and commercial DNA microarrays suitable for ChIP-on-chip.
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